Acronyms or abbreviations in titles are usually discouraged, but it is best to check with the journal. Some journals provide a list of standard abbreviations that do not need to be defined. It depends on the target audience of the journal.
In principle, it is better to avoid in abbreviations in title and abstract. For some reason, you can use abbreviation in your abstract by first writing the full text and following the abbreviation in a bracket. Then after, you can use the abbreviation explicitly.