There are many ideas to create genetically modified microalgae for higher productivity,
Why are the reports on this so little?
I think now it is more possible with CRISPR technology.
Any idea of what are the barriers?
Yes, it is very much applicable.
There are several algae specific CRISPR methods and papers are available.
For instance,
1. A CRISPR/Cas9 system adapted for gene editing in marine algae https://www.nature.com/articles/srep24951
2. Ajjawi, I., Verruto, J., Aqui, M., Soriaga, L. B., Coppersmith, J., Kwok, K., Moellering, E. R. (2017). Lipid production in Nannochloropsis gaditana is doubled by decreasing expression of a single transcriptional regulator. Nature Biotechnology, 35(7), 647–652. https://doi.org/10.1038/nbt.3865
You can also refer this recent review paper for more details.
Application of the CRISPR/Cas system for genome editing in microalgae https://link.springer.com/article/10.1007%2Fs00253-019-09726-x
You can read the following recently publish review article, where you could get your answer as yes:
Application of the CRISPR/Cas system for genome editing in microalgae https://link.springer.com/article/10.1007%2Fs00253-019-09726-x
Thanks for the answers, I have read all the papers in this topic. When I consult with people how haven't done the project, they say it it very difficult to get result. But when I read the papers it seems it is doable and there is chance, specially with recent progress it is more promising. Unfortunately, couldn't get any comment from experienced people.
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