Some pharmaceutical companies combine myo-inositol and folic acid in a single dose. Is this safe for those with the MTHFR mutation?
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MTHFR is a gene . We all carry two copies of MTHFR. MTHFR tells our body how to create an enzyme involved in breaking down the amino acid homocysteine. As is true for any gene, the DNA code of the MTHFR gene can vary. ... There are two MTHFR gene variants, called C677T and A1298C, that have been an active area of study.
MTHFR mutation with the omocisteine's value is really important in clinical history of recurrent miscarriage
Currently, the best forms of folate available as supplements are salts of 5-MTHF, and 5-MTHF is bioidentical to naturally occurring folates in foods.
Many supplement companies have replaced folic acid with these forms as they can be utilized regardless of mutations on MTHFR.
Also, 5-MTHF entry in cells is better controlled than folic acid, which can support excess cell proliferation.
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