The elementary question, Cahit Canbay, seems to be what you regard as MS-specific, and on the basis of which exemplary or archetypal MS cases or specimens you do so. I seem to have first compiled these pieces of evidence.

What I found to be exclusively peculiar to MS were anatomical pathological/MRI findings which appear easier to be understood by venous pressure field gradients than by electric corpuscular field gradients.

Thank you for interested in the issue, Franz Schelling, I have researched at 14 different aspects of MS disease for many years. I think you've read 11 approaches from current publications!. In particular "canbay Faroe" can be found when you write in the search engines are given in summary there. A visible example of the effects of dielectrophoretic fields can be seen in "canbay cytokine". Venous pressure field gradients are currently related to the operation of the venous system and the changes in the particle parameters in blood.

The issue is Dawson fingers, in which the dielectrophoretic effect is shown to cause these finger type appearances. The article is about to be published. It was also shown in another publication that Kurtzke's epidemiological studies were reliable but their inferences were inaccurate. My work on why MS affected women more was sent to journals. I know this is a very difficult process.

Another important information with respect to MRI; Is RIS a correctly defined concept? According to my theory, there is no this kind of syndrome called RIS. Dielectrophoretic force is also the cause of MS-like effects in MRI scans, which is more common in MS patients. You will see an objective assessment on page 6 and 7 of "canbay faroe". If we follow objectively the scientific laws, they lead us to real solutions.

Please, Cahit Canbay, be so kind as to check the evidence given on the venous origin of cerebral Dawson's fingers and the evidence given for the ligamentous origin of the spinal cord lesions which originally defined MS. I ad what 38 years of topical research have presented to me and am happy if you might show me some complementary or conflicting piece of evidence.

I wonder about the opinions of all scientists as to whether I have a concept called RIS, as I have asked before, and as I have explained showing with my studies, does not exist such a concept. To claim that MS is a too complex disease, deriving new concepts, it does not provide a benefit to MS patients.

Wirchov Robin spaces is a reality, but I would like to explain in parallel to my theories that Dawson fingers are an indication of the susceptibility to MS. But I don't want to spoil the original because I sent it to a journal to be published. In addition, Dawson fingers-like images may appear around the CSF, and especially where I expect.

Cahit Canbay, the concept of a radiologically isolated syndrome is a clinical farce - which ought to be clearly evident on everyone who knows what I ever wrote on the topic. Why not have a look at the findings which originally defined MS (www.ms-info.net)? or their identification in my recent book?

Franz Schelling, if the goal is to find a cure for MS patients, it should be to reveal the cause of RIS. I am interested in the main causes of the findings, not to draw conclusions over the findings. The main problem is examine of the reason why the occurrence of MS-like syndromes after and during MRI scanners and applications contributes to the etiology of MS? Would RIS has any meaning if it wasn't exist the MRI scanners? My claims and evidence are that the electrical field properties of the RF coils create RIS.

Cahit Canbay, all I know of RIS are the criteria some clinicians have agreed to be required for making the diagnosis RIS - and the same applies to CIS and any form of CD (clinically defined/definite) MS.

Which of the MR scanners' lasting or pulsating electric field properties can be shown to determine the presence of a RIS?

The clearly specified anatomical MS pathology plainly recapitulated in my writings demands the existence of forces being exerted on the part of definite veins.

This is to be directly shown in the brain (the given handout is a briefing on my presentation given at the ISNVD meeting of SF, CA, in 2014).

As I said, for a better understanding of MS, there is a need to know the main reasons. I am expressing the etiology of MS. In explaining my theory, I can also clarify the issues that are considered as unknown to all about MS, and I prove it. I never blame neurologist scientists. I appreciate their some efforts. But, the whole human body is an outstanding engineering monument created and left to evolution. I just want them to see their perspective on MS from my point of view. Until today, no scientist has looked at MS like me. If they had, they would not start each time, saying, "The main cause of MS is unknown". Only artificial electromagnetic field sources are not reason of MS. In ancient times, the sources of the electromagnetic field for MS were human themselves and the natural e.m.f sources. Now all the electromagnetic field sources.

Had you had a look in my book on "Multiple Sclerosis & CCSVI", Cahit Canbay, but the 5 pages of its 5th or 6th chapter, or even the 14 pages of its 2nd, this fact ought to have become obvious to you: The bypassing of any MS-specific finding on the part of clinical neurology ... plus its deplorable consequences (please check my quotes of famous neurologists!).

As for electromagnetic sources causing MS: Did you specify which source causes which MS, and how?

The “chronic cerebrospinal venous insufficiency (CCSVI)” especially occurred in internal jugular veins has been shown as the cause of MS. But this is not true completely. Particle accumulations may appear in brains, spinal cords and jugular veins of MS patients where appropriate conditions. These may be symptoms of MS. This accumulation in internal jugular veins is caused by dielectrophoretic force in the brain (because the blood flow rate is less than that of the arteries, the velocity gradient across the venous stenosies can be significantly lower) and if these vessels are opened by drainage (firstly as Zamboni did), the patient can relax for a long time. As seen, this particle accumulation is not the main cause of MS. The venous stenosis are not the cause of MS but products of MS.

The main reason for accumulation is the dielectrophoretic force, as I have stated in my theory.

Hasn't all too much stated about MS, Cahit Canbay, that has not been secured by solid foundations? The MS specific findings shown in the "Multiple Sclerosis & CCSVI" book are seen to be necessitated by the indicated venous pressure fields.

Why not make plain which MS specific findings necessitate the postulated accumulation of dielectrophoretic forces?

Otherwise the confusion about the subject cannot but increase.

I have clearly written the validity of the Bernolli principle in a fluid channel. When the fluid velocity decreases, particles tend to accumulate and the dielectrophoretic force also contributes to this accumulation. Particularly in white matter and spinal cord, MBP is separated from the myelin sheath and collected in certain places. Thanks to the direct dielectrophoretic force. Nobody could explain this happening with the findings. You can understand, why I could propose this theory. You can find the effects that cause the event with long-term computations, which you cannot realize with the naked eye, without making any omission in the accounts. These are the facts that I have revealed at the end of long processes at every stage. Scientists can see clearly if they look at the subject objectively.

Although the attached study is not directly related to MS, it is indicative of how and why the dielectrophoretic force forms cytokine-like formations on T cell models. Please, zoom the pictures. This approach is also a first study in the literature.

Please, Cahit Canbay, come to the point: Why do the Dawson's fingers emerge only from definite zones of their lesion/central veins, and this only in particular cerebral venous compartments ... leading to such grotesque vein-deformations as shown by Putnam and Adler, and vein wall thickenings, as shown by Colin Adams?

Why cross spinal MS lesions the cord from side to side/posterior midline?

Please, Franz Schelling, I saw and appreciate your endeavors on MS. I would like expressed excluding you:

I understand why most concepts in medicine have not been deeply studied. Because most of researches are done in accordance with the demands of pharmaceutical companies.

1. I think you've clearly noticed how the dielectrophoretic force causes cytokine-like formations.

2. Why, MS disease is more common in Faroe islands, why is not widespread in Africa, South America and some places? I explained extra, why MS would be higher on the Sardinia island, even though it was not related with places in terms of geography where MS prevalence higher .

3. Why Dawson fingers do not appear more in African residents? They don't have Virchow - Robin spaces in their brains?

As I said before without giving detail, during and after brain MRI scans, these finger-shaped formations can be occurred in regions which have higher conductivity compared to around them such as ependymal surfaces, wedge-shaped discontinuities, near the blood vessels, posterior and anterior horns. Brain medium is heterogeneous medium. If you look at Dawson's fingers in micro level, you can see more discontinuity effects of micro structures.

4. As a neurologist, have you ever considered, why you recommend a 3 T MRI to diagnose MS for your patients? Their answers are given in my theory. All my studies on open access websites.

It's a pity venodynamics is far less researched than the behaviour of electric and magnetic fields, Cahit Canbay - except you speak of the latter as effects of the former. Which would unduly complicate things.

Let's agree that we need better approaches to curing MS, and do our best to come closer to this goal.