Is there a tool for 3D miRNA modeling?

For example for an interaction study between a protein target.

22 November 2020 3,952 4 View

New network testing models for deep learning in biological testing ?

We tested four models: logistic regression (LogReg), multilayer perceptron (MLP), graph convolutional network (GCN), and edge-attention graph convolutional network (EAGCN). Are there other models...

08 November 2020 2,347 4 View

Where to find cancer datasets composed by clinical markers and gene expression levels?

Currently, I am validating a new machine learning approach. But, I need to find different cancer datasets composed by clinical markers and gene expressions. For now, a just found MMRF data set...

11 October 2020 9,012 2 View

Can I use a Glass electrode (standard used for pH measurement) for measuring ORP?

I have made a test to investigated: I measured the potential in mV of a standard +220mV solution using my pHmeter which gives a mV value with the pH. The result was +9mV. But this was the result...

06 October 2020 7,220 3 View

How to do validation on a new instrument?

Halloo scientists, please help me the procedure s on doing validation on new bought instrument/equipment before starting doing analysis

07 September 2020 1,590 3 View

Can my RNA interference have any influence in my endougenos control gene?

Good night all. I'm using RNAi to knockdown a transcription factor from a primary cell and I need to validate by westernblot. With Ponceau marking i can see that i'm putting the same amount of...

25 August 2020 263 3 View

How can I hide nodes with posterior probability under 0.5 in BEAST phylogenetic tree visualization?

06 July 2020 1,376 6 View

How do I stored nano particles in my workplace and how long?

I am looking for a technique which is used to store the nano particles without any property change.

23 June 2020 2,473 15 View

List of environmental journals with no publishing fees?

I'm looking for a well-indexed Environmental/ocean science journal to publish my research papers without any publication fee, could you help me?

20 May 2020 2,233 14 View

Validation set error is high in deep learning using Keras/R, how to fix it?

Hello, In these days i'm trying to train a deep neural network with a matrix with 14382 variables x 671 cases, from IV spectral data. I'm using R with Keras package (compile and execution commands...

07 April 2020 8,098 7 View

Do I need to do linear regression before running mediation analysis using PROCESS MACRO by Hayes ?

I just wanted to check if I need to run a linear regression separately if I am using PROCESS MACRO to run mediation analysis. Thank you.

02 March 2021 4,359 3 View

What SPSS analysis should I run with one IV (with two levels) and two DVs?

Hi, I am trying to figure out which test would be most appropriate to run for the following question: Is there a difference in task blood pressure between smokers and non-smokers? There are two...

01 March 2021 8,235 2 View

Mediation path analysis - Can I run two seperate models?

I am wanting to run a serial mediation model with 2 x IVs, 2 x MVs, and 3 DPs (all continuous). Is it problematic to run 2 different models for each IV, keeping the MVs and DPs the same in each...

27 February 2021 5,681 3 View

SEM or Multiple Regression for an analysis without Latent Variables?

Hello, I have three hypothesis to test, all with the same IV. I am testing if the effect of the IV on the first DV is mediated by awe. I am then measuring whether the effect of the IV on a...

26 February 2021 8,399 5 View

Are there lab markers/pens resistant to Roti-Histol?

Hi, I'm looking for a pen/marker to write on the smooth, transparent (non-frosted) part of microscopy slides which does not get washed away by alcohols and most importantly Roti-Histol. I want to...

24 February 2021 9,902 5 View

Why anti-CD20 or other antibodies are not used to label target cells in flow cytometry t-cell cytotoxicity assay?

New to the field of cell therapy. Why fluorescent-labeled antibodies to target cell antigens are not used for determining target cell count by flow cytometry in cytotoxicity assay (eg car-t)? Cell...

21 February 2021 3,278 3 View

How can we estimate sample size for a moderated mediation analysis with more than two mediators?

How can we estimate sample size for a moderated mediation analysis with more than two mediators? I am looking for scripts, macros, syntaxes, that allow us to estimate sample sizes for research...

15 February 2021 6,813 3 View

What does it mean if in mediation analysis the indirect effect is significant but is a larger b value than that of the direct effect?

I understand that for partial mediation to have occured the CI for the indirect effect must not cross zero and the b value for the indirect effect should be smaller than the b value for the direct...

14 February 2021 3,273 7 View

Can we have a model where A affects B which affects C but B is not a mediator?

Please suggest any papers in Information Management area that have the model where A affects B which affects C but B is not a mediator? What is this relationship called?

13 February 2021 5,239 3 View

What is the step by step process involved in interpreting the results of mediation analysis done using PROCESS macro?

09 February 2021 7,377 2 View