It is nitration reaction and using the reagents such as nitric acid, acetic acid or acetic anhydride and sulphuric acid
In principle it will be a very simple nitration reaction.
Considering that the 5-position is meta to the deactivating (m-directing) acetyl group and para to the strongly activating (o,p-directing) hydroxyl group, a direct nitration (with sulfuric and nitric acids) will result in the desired product with no significant side reactions.
Use a normal procedure to nitrate aromatic compounds. Considering that the starting material is a solid (is it?), an inert solvent should be used; maybe an alkane (if soluble) or acetone.
direct reaction between 2-hydroxyacetophenone with nitrating mixture you will get desired product
hi, you can use this method "http://www.orgsyn.org/demo.aspx?prep=CV2P0434"
however, it is preferable to use a solid support (acidic clay) to direct the reaction towards the least hindered product
The reaction that you want is shown in page 17 of this patent application (Example 1:A1)
https://patents.google.com/patent/WO1998044920A1/en?oq=wo++9844920
Good luck
direct reaction between 2-hydroxyacetophenone with nitrating mixture( of concentrated sulfuric acid and nitric acid) you will get desired product
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