My group synthesize organicmolecule then incorporale onto the silica gel surface. I wonder how to improve the efficancy of bonding between the SiO2 surface and the organic molecules that are rather big and non polar. (Thank you very much for your kindly reply.)
Omar Gonzalez-Ortega
Silanize the surface with a silane containing a hydrophobic group.
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Abdelhak Maghchiche
To improve bonding between SiO₂ and nonpolar organic molecules, modify the silica surface with hydrophobic groups like alkylsilanes or apply polymer coatings to enhance compatibility. Use ligands or optimize reaction conditions (e.g., solvent polarity) to facilitate effective grafting of bulky compounds onto the silica surface.
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