I have a plant which has amount of indole acetic acid and I want to convert this amount to indole alkaloid .......... what is the precursor or any substances can be added to make this action ?
The biosynthetic pathway indole alkaloids in C. roseus has been investigated for many years, but the whole process is not completely understood. Overall, three stages could be recognized in the biosynthesis of bisindole alkaloids: (1) Formation of tryptamine and secologanin: Tryptamine is biosynthesized from the shikimate pathway and secologanin from the terpenoid pathway; (2) Formation of monomeric alkaloids: Tryptamine and secologanin are combined to form strictosidine, which is further converted to monomeric alkaloids like vindoline and catharanthine; (3) Formation of bisindole alkaloids: Vinblastine and vincristine synthesize from the coupling of catharanthine and vindoline