How to compare the diagnostic performance of a test on two different samples?

26 May 2020 1 901 Report

Could you help me out how to compare the sensitivity, specificity, PPV and NPV of the same diagnostic test (vs. a gold standard) on two different samples/populations?

Presumably I should use chi square test, but I don't know how, as these are all derived parameters, not percentages. Preferably I would use SPSS.

Answers are much appreciated!

Ángel Herráiz-Adillo

Dear Mihály Károlyi,

Perhaps,the thread started by Katrin Skerl "How can I compare 2 AUC values of different parameters of the same sample group (ROC analysis)?" on May 11, 2015 can help you.

Best regards

Badges
Science topic

More Mihály Károlyi's questions See All

How would you model a light chain only antibody based on known sequence?

I am curious whether it is possible to download the pdb file of a mouse kappa light chain, and change the residues (mainly CDRs) to that of my light chain's in order to obtain a plausible 3D...

19 April 2016 9,469 3 View

Can anyone suggest the values for surface roughness coefficient of cauliflower and potatoes?

I need the values to explain the wetability properties.

24 April 2014 5,736 1 View

How to compare two groups with only two measurements?

Hiiiii everyone! I have an enquiry on statistical analysis. I was looking for many forum and it's still cannot solve my problem. I want to compare means of two groups of data but only with two...

03 March 2021 8,796 3 View

Can we classify HV and LV lines based on line length?

I have dataset which shows the length of power lines. I need to classify the lines based on the line length. Is there a rule to classify the High voltage (HV) and low voltage (LV) lines based on...

03 March 2021 4,116 4 View

What SPSS analysis should I run with one IV (with two levels) and two DVs?

Hi, I am trying to figure out which test would be most appropriate to run for the following question: Is there a difference in task blood pressure between smokers and non-smokers? There are two...

01 March 2021 8,235 2 View

What test should I use to compare two or three means, if data is not normally distributed but sample size is > 30 in each group?

I personally feel this as a most confusing question. As per my understanding, if sample size is > 30, and sample is skewed, we can still use paramteric approach, as it will follow Z...

01 March 2021 1,587 6 View

Distribution of particles in metal matrix?

How would define the "good" and "poor" distribution of particles within the matrix. Is there a quantitative solution to assess the distribution of the particles, which then having denotation of...

28 February 2021 7,397 8 View

Statistics: include groups of respondents made by one person for analysis?

Good morning, I could not find literature about this so I am asking. I am organizing data for a questionnaire (N=100) that foresees some personal questions like level of education. For the aim...

25 February 2021 2,090 4 View

Sample size determination for non-parametric tests?

How do I run a a priori sample size determination for non-parametric tests, like the Mann-Whitney U-test and the Kruskall-Wallis or other non-parametric tests that accord with the unpaired t-test...

24 February 2021 166 6 View

How to examine multicolineairty in backwards regression with binary variables?

I did a backwards regression with various binary variables, but some of the binary variables are negatively correlated with the outcome, which would make no sense cause the correlation univariate...

21 February 2021 4,392 3 View

Statistical Tests for Quantitative Study?

Hello Everyone, I have one population, sample size 200. and needed to find the correlation between Variable A and B. Also, which T-test should I choose for hypothesis testing Please advise...

21 February 2021 7,591 4 View

How to model rupture in geogrid in abaqus?

Hi researchers I wanna model tensile test on geogrid in abaqus, so I added displacement to one side of geogrid and the other side of geogrid is constrained completely, everything seems normal but...

19 February 2021 2,195 2 View