We find the article of Jirkof et al (2019) but they use buprenorphine during only 3 whereas we would like to keep bupreorphine in water bottels during 5 days.
Given these findings, it's advisable to prepare fresh buprenorphine-infused drinking water for mice at least every 24 to 48 hours. Using glass containers and protecting the solution from light can help maintain the drug's stability. Regularly monitoring the solution for any changes in appearance or efficacy is also recommended to ensure consistent dosing