How does (early stages) Parkinson's disease affects neuronal microstructure that MRI would be sensitive of?

11 November 2017 0 4K Report

What is the effect of Parkinson's disease on neuronal microstructure?

I am looking for MRI-sensitive markers, for example axon size, myelin content, iron load, neuromelanin changes? Any other significant changes on neurons microstructure due to Parkinson's disease?

I am not looking in the Substantia Nigra.

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