I am looking for an unbiased way to look for the genes involved with CNS.
I am interested in prioritizing the list of CNS genes for my studies.I had been looking at different ways of prioritization and looking for any other information from the experts in the field.Is there a way to prioritize the CNS genes ?
Are there any gene panels,databases with information only for CNS related disorders ?
What would be the best systematic way to reach up to top 50-100 genes involved with CNS development,give the complexity of development. ?
Any help and suggestions are highly appreciated and welcomed.Thanks a lot in advance.
Thanks
There is a great web-based tool called phenolyzer. It accepts a list of HPO terms, or disease terms as input and provides a regression model to rank disease genes. It is well documented so that you can adjust parameters to your specific focus. Links are to the web sever and the paper published in nature methods. Hope this helps!
http://phenolyzer.usc.edu/
http://www.nature.com/nmeth/journal/v12/n9/abs/nmeth.3484.html
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