I am interested in developing a monoclonal antibody against the human blood group A. Can anyone help to obtaining Glycoprotein fraction isolated from the saliva of secretors with blood group A, to be use as immunogen?
Thank you in advance.
Challenging. Given it is a sugar moiety. May be able to have some chemical companies build the structure on a carrier protein for you
I do agree with Jody.
However you can have some cue from this paper:
J Biochem. 1975 Dec;78(6):1207-14.
Blood group A activities of glycoprotein and glycolipid from human erythrocyte membranes.
Yamato K, Handa S, Yamakawa T.
Do you need human or mouse mAbs?
Thank you very much Piero. I would like to develop mouse mabs as a tool for blood typing group A.
Probably you are aware of this, but Sigma is already selling a mouse mAb
http://www.sigmaaldrich.com/catalog/product/sigma/sab4700674?lang=en®ion=US
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