I mean, I look up in the solvent impurities charts but they show "–" under D2O for solvents which are immiscible with water, such as chloroform, cyclohexane or di-clo. But actually, you can dissolve like 1-2% CH2Cl2 in water or deuterated water. That is in the range of 0.1M! If my D2O-dissolved sample is contaminated with CH2Cl2, where should this peak be, provided there is a peak for CH2Cl2 in D2O?
Thank you
Still there is a least chance to get that peak. But in that case other than compound peak you can see a singlet peak between 4.5 to 5.5.
Definitely yes; the peak is MOST likely to be easily distinguishable from water (different location, no exchange, much narrower) and if your S/N is good enough (at 1% it should be!) you should see its 13C satellite peaks (probably about 110 Hz on each side). If the stuff really dissolves, there is no way you can miss it.
Btw, if you work at pretty high field (>= 500 MHz) and achieve an exceptional resolution (
Yes dichloromethane show a signal at 5.29 ppm and solvent independit
For more detal see this article
NMR chem shift of trace......
Organometallics 2010.vol.29 pp2176
- Badges
- Science topic