During optimization of binary feed (azeotropic) distillation column MINLP is needed.
In this article (section 3.2.2):
http://www.midaco-solver.com/data/pub/The_Oracle_Penalty_Method.pdf
some distillation column sequencing benchmarks (formulated as MINLP) are solved.
While using chemcad I found that customization is required for simulation of hybrid separation (combined distillation and membrane).
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