yes, it has a very interesting postoperative results...all recent studies support it use as it has neuroprotective effect except a single study in turkie at 2008 .

I have used clonidine intrathecally extensively but not dexmedetomidine. It's been tested many times, for example:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819844/

http://www.ncbi.nlm.nih.gov/pubmed/21897504

http://www.ncbi.nlm.nih.gov/pubmed/16430546

It appears safe and efficient.

Thanks,

Matthieu

Thank you Dr.Khaled Al Zaben

Thank you Matthieu,I advice you to use it and compare it with clonidine ,you will see big difference!

I will try. Wich dose?

Dear Luis , you can use 0.5-1 mic/kg.

thanks

exmedetomidine dose of 0.5-1 mg / kg epidural / caudal provided in local anesthesia, a reduction in local anesthetic, improves motor blockade without hemodynamic repercussions. I have no experience intrathecal use.

Thanks Enrique Calderon

 Dexmedetomidine dose of 5-10 mcg add to bupivacaine %/5  in subarachnoid route successfully without any appreciable side effects.reduction in local anesthetic, improves motor blockade. increas analgesic duration and without severe  hemodynamic exchenge