I am presently using PLGA (50:50) Polymer with inherent viscosity of 0.21 for my project. But I have another PLGA (50:50) sample with Molecular wt 15000 Da. So can I use it as such?
I believe you are talking about intrinsic viscosity and sure you can calculate mol wt using some mathematical formula using glass viscometer knowing the dimension of the tube and time. You consult any basic polymer or physical chemistry book.
As Dr. Ahmed mentioned, it is intrinsic viscosity and needs special equipment. For more information, you can find our publications on CMC and cellulose which intrinsic viscosity has been used to measure MW.
As I mention above is the inherent viscosity not the intrinsic viscosity. Inherent viscosity is the ratio of natural log of the relative viscosity to the mass conc. of polymer. And Relative viscosity is the ratio of viscosity of the solution to the viscosity of solvent. So if I know the solvent and polymer conc. used to determine inherent viscosity by the manufacturer I can calculate inherent viscosity using Viscometer. But Here I am asking for: as we can convert intrinsic viscosity to MW of polymer using Mark-Houwink equation...similarly is there is any way to directly calculate MW from inherent viscosity using similar kind of equation?
The answer is NO, you can´t do that, at least using just one value.
You could calculate the average viscometric Mw only if you have inherent viscosity data for different polymer concentrations at the same temperature with same solvent. Then extrapolating the inherent viscosity at cero concentration value you will obtain the intrinsic viscosity value that you can use to calculate Mv using M-H equation.