In the era of information and reasoning, we are shown several scientific pieces of information either in print form or online globally. Despite the appreciable access to information the originality, novelty, and quality of information are substandard. For example, a large number of researches done in the developing world are either published in reputable journals or on the shelf. However, implementation of these research findings is scarce.

This could be due to data quality or the quality and quantity of the research team involved. The Issues that could affect the quality of research in developing countries include but are not limited to;

· Availability of limited resources to support research projects

· Inadequate time devoted to research projects because people who teach at the university level in developing countries are rarely full-time professors and usually have several jobs.

· The theoretical nature of research methodology in the curriculum, so students become professionals without the practical knowledge of how to do research.

· Limited access to journals, search engines, and databases and high subscription cost that is beyond the reach of the budgets of both individual professionals and university libraries.

· Weak ethical review committee to verify ethical treatment of human subjects.

· Rationing research funds to several colleges and department, which lead to limited competition and an increased chance of doing weak research

· Weak institutional structure and lack of empowerment to research staff

· Poor data management systems and lack of databases

· Availability of poor research guidelines and poor composition of the research team (i.e. failure to involve all relevant expertise in developing proposals and conducting analysis and interpretation of findings)

In the face of the above challenges, using real-world health be a solution to data quality problems? If, what are possible changes using real-world health data in developing countries?