i have to use indium chloride in organic synthesis. but avilable chemical is indium chloride tetrahydrate. can i use it with the change of calculations
That is possibly depends on the type of chemistry that you have supposed to perform. If you are to conduct a moisture sensitive reaction for example, you are to use anhydrous indium chloride. Usually hydrated indium chloride is enough to perform the reaction that is insensitive to moisture. Calculations can be made accordingly. The following article may help you more for your quest:
Article Recent Developments in Indium Metal and Its Salts in Organic Synthesis
Azeotropically can be dehydrated with solvents like n-butanol,heptane or toluene going beyond 95 °C.
Then with no doubt you can use hydrated indium chloride. If you use anhydrous that also become hydrated in water. There is is no meaning to use anhydrous salts in water.
If the reaction condition is not dry, then the hydrated salt can be used as it is, but do consider the weight of the coordinated water molecules while calculating the amount of the catalyst. Also for the reaction in dry condition, the hydrated salt can be used after drying(under reduced pressure and 100C temperature for 24 hours)
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