Can anyone suggest the best optimum conditions to produce 5-(hydroxy)methylfurfural from fructose?

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Selvaraju Sivamani

I guess there is a problem with stoichiometry. Molar ratio of fructose to inorganic catalyst should be 2. Check your stoichiometriic ratio.

Teodoro S Kaufman

5HMF is cheap and commercially available.No need to waste expensive fructose

Korrapati Suresh Babu

I think if we use catalytic amount of strong acid along with ethanol reflux, we can get 5-(hydroxy)methylfurfural.