Numerous studies have proven that Cannabis has anti-cancer effects. I was wondering if there is a chance to remove its psychoactive effects in order to release a strain of Cannabis plants that can be used more freely in the medical field. Thanks!
Dear Rene,
CBD is one of more than 80 active cannabinoid chemicals in the marijuana plant. Unlike the main psychoactive cannabinoid in marijuana, tetrahydrocannabinol (THC), CBD does not produce euphoria or intoxication. Cannabinoids have their effect mainly by interacting with specific receptors on cells in the brain and body: the CB1 receptor, found on neurons and glial cells in various parts of the brain, and the CB2 receptor, found mainly in the body’s immune system. The euphoric effects of THC are caused by its activation of CB1 receptors. CBD has a very low affinity for these receptors (100 fold less than THC) and when it binds it produces little to no effect. There is also growing evidence that CBD acts on other brain signaling systems, and that these actions may be important contributors to its therapeutic effects.
The publication contained in the following link sheds light on the recent updates on CBD:
https://www.drugabuse.gov/about-nida/legislative-activities/testimony-to-congress/2016/biology-potential-therapeutic-effects-cannabidiol
Hoping this will be helpful,
Rafik
I appreciate your question. Please consider looking at THCA, the precurser to decarboxylated Delta9 THC. Many patients are using it for pain, inflammation and are also trying to use it when the psychoactive Delta9 THC is just too much for them. Because there have not been significant studies, I think it is a prime area for research. At least in pain and inflammation and spasticity it appears to be almost as effective as D9 THC, in anecdotal evidence. But I am wary about anticancer unless we see good studies ~~ please! What an exciting field this is.
- Badges
- Science topic
- Similar topics
- Biological Science
- Plant Sciences
- Ethnobotany
- Natural Product Pharmacology