Are there any publications about the seizurogenic effects of low-dose naloxone in tramadol overdose?

07 July 2016 0 366 Report

A colleague recently attended a live CE put on by American Pharmacists Association where the presenter verbally advised against the use of naloxone in tramadol overdose. I have only been able to find (potentially) one study on this particular claim (specifically in doses of 0.8mg or less of naloxone)...most of the studies have actually suggested a protective effect. Any information would help. Thank you

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