Are there any alternatives to EDCI in the esterfication?

03 March 2019 1 592 Report

I am doing esterfication ( steglish) for 9-bromonanoic acid using ( EDC/ DMAP) in DCM. and I want alternative to EDCI.

In organic solvents, dicyclohexyl carbodiimide (DCC) is frequently used for such purposes. The byproduct precipitates and can be easily removed by filtration. It is important to use dry solvents and reagents.

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