Are EC50 values in nano- and pico-litre cultures comparabe with EC50 values from µL and mLcultures?

12 December 2017 0 697 Report

Hi there! I am setting up a screening of cells in nano- and picolitre cultures and I see that my EC50 values vary some time from the µL and mL screens. Is this completely a question of inhibitor adsorption to the material or may some other reasons play a role as well? What are your experiences with these volumes?

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