How can be opened the ring of a 1-methyl 2-Imidazolidinone obtaining the primary amine? The reaction must occur in bulk...
Thanks!!
For urea, aqueous NaOH hydrolysis at 100C has been reported. see J. BIol. Chem, 1942, p705. For your System, hydrolyis in Ethanol/water under with NaOH might be effective see the attachment. The imidazolidinone might be harder to hydrolyse.
First of all, thank you all for the quicky reply
Unfortunately I can't use HCl and aqueous NaOH.. the main issues are the conditions of reaction: I have to prepare polymers in bulk at High T (around 200°C). Preparing polyamides, I have organic acids and amines plus just a bit of Cat. (Lewis acid) ... I Know that imidazolidinone is pretty hard to be opened due to its stability, but in my trials I found that in small quantitative it's possible (titrating a solution obtained from my polymer, I found interactions beetwen acid terminations of my polyamide and imidazolidinone) and I'd like to emphasize this by-product formation...
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