As the COVID-19 outbreak unfolds, CDC had recommended to provide HEPA or equivalent filtration of airflow exhaust for mechanical ventilation.

· For mechanical ventilator we set up "closed" system. but is it necessary to add on inspiratory HEPA filtration? or to change HME to HME F(with HEPA) if there's already had exhalation high efficiency filtration?

· For intra hospital transport patients on transport ventilator , knowing should prevent for those confirmed coronavirus with the HME F(with HEPA) on patient , do we need to add HEPA filter at the air entrains to protect patients from breathing in any infectious from the environment? regardless of HME or HMEF, this could also prevent machine contaminated by room air. ?

· Any ventilator disinfection guides after using on COVID-19 cases.?

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