Abstract
Ficus carica Linn. (Moraceae) is commonly known as edible fig. Due to the useful effect of leaves in skin diseases, pharmacognostical standardization of F. carica leaves was carried out. Morphological examination showed that leaves are long, palmate shaped and dark green in color. The leaves powder had characteristic odor and taste. Transverse section of leaves showed upper and lower epidermis with covering and glandular trichomes and midrib showed arc shaped vascular bundle. Successive extractive value was highest (23.606%) in case of aqueous extract. Mean ash values (%) were 23.04 (total), 6.48 (acid insoluble) and 12.69 (water soluble). Loss on drying was 5.9107%. Resin content was found 1.33%. Phytochemical screening of leaves powder showed the presence of carbohydrates, phenolic compounds, flavonoids, steroids, tannin, resin and acidic compounds.
Please give idea some journal which are published full article.
Dear Researcher
I am attaching some article that may help you. also look below abstract.
Farmaco Sci. 1982 Jul;37(7):475-85.
[Determination of the coumarinic constituents of Ficus carica leaves by HPLC].
[Article in Italian]
Innocenti G, Bettero A, Caporale G.
Abstract
The coumarinic compounds of fig leaves (Ficus carica) here examined closely. The furocoumarins psoralen, bergapten and the coumarins umbelliferone, 4',5'-dihydropsoralen and marmesin are present. These substances were determined in a "coumarinic extract" by high pressure liquid chromatography (HPLC). The seasonal variations of the above mentioned compounds were also studied in a series of samples of leaves picked from the same plant, at regular fortnightly intervals during the period 1/VI-2/XI/1979. From the data obtained it is noticeable that the total coumarinic content is maximun--0.5% as compared with the dry weight--in the extract of leaves picked on the first August, while it is lowest in the extract of leaves picked on the 15th June. The quantity of psoralen is always greater than that of bergapten, umbelliferone, 4',5'-dihydropsoralen and of marmesin. The ratio psoralen: bergapten is not constant, but fluctuates extensively with the seasonal variations from 2.8 to 7.7.
PMID:7128806 [PubMed - indexed for MEDLINE]
Dear Researcher,
Development of quality standards (QS) for a herb is an important issue in herbal science.
Every plant must have QS before further research on that plant is undertaken.
If you do good study you can publish quality standards work in Journals like Brazilian Journal of Pharmacognosy etc.
Also refer ICMR book Quality standards on Indian Medicinal Plants.
Proud to say i have contributed for development QS for about 50 Indian medicinal plants you can find my name in Vol 7 to 13 of the ICMR book.
Find a similar work (QS) done for a polyherbal formulation by me in my list of papers.
Hope these info are helpful.
you can add pharmacognostic standards specific for leaf drugs like :leaf constants such as stomatal number, stomatal index etc.
1.Quality standards of any herb/plant confined to few pharmacognostic parameters only which do not really provide true standards as this plant grows at different altitudes and bound to have seasonal and geobotanical impact on phytochemical concentrations .It would be helpful if you can focus on this aspect and develop good quality standards parameters.Some useful ref. in this aspect is:
1.www.herbcyclopedia.com › Home › HEALTH BENEFITS
Mar 18, 2015 - The leaves of ficus carica experience a change over time, changing .... [2] Anti-inflammatory and antioxidant activity of Ficus carica Linn. leaves.
Referring to the following docs may be useful to you:
1. WHO Guidelines on standardization of medicinal plants. PDF file of it is available free of cost.. The most important thing is to examine the sufficient no of the samples collected across the distribution range of the plant species as advised in the guidelines.
2. HPTLC Atlas of medicinal plants published by CCRAS.
Hope the info will be of help toyou.
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