Dear Linas Jurgutis,

African swine fever virus (ASFV) causes a lethal haemorrhagic disease of swine which can be transmitted through direct contact with infected animals and their excretions or indirect contact with contaminated fomites.

Thermal treatment may cause degradation of organic compounds present in the slurry. Also the hydrocarbon vapors will be released and microbial activity may be reduced.

Although, lime can be used as a disinfectant for pig slurry contaminated with African Swine Fever.

You can google it.

Good luck.

Dear Pankaj Kumar,

I understand the heat treatment working principle.

The question is more about: whether or not thermal treatment destroys ASFV virus. In case it destroys, which is the regime (conditions) and any publication stating/proving that?

Thanks,

Linas

Dear Linas Jurgutis,

What temperature are you going to consider? Low thermal treatment may not completely kill the virus. Also, if you used high temperature the slurry may be denatured.

Pankaj Kumar,

A temperature needed to kill the virus. ;) We can inoculate with active seed from the other biogas plant - no problem.

Still, my question remains: how to kill the virus, which are the conditions ? Any publications about this problem solution?

Generally, high temperature makes the viral genetic material and its internal proteins deactivated and do not kill virus.

How is therapeutic antibody progress?

We used the mouse monoclonal antibody for in vitro assay. It works well.

African Swine Fever Virus (ASFV) p30 Monoclonal Antibody

http://humimmu.com/african-swine-fever-virus-asfv-p30-monoclonal-antibody.html