When I injected 2 g/kg pyruvate into SD rats, they contorted their body into painful postures and 30 minutes later died. Why?

In our previous studies, we found that the gluconeogenic genes (G6Pase and PEPCK) were down-regulated in KO rats compared with WT controls. Consequently, we performed the pyruvate tolerance test...

09 January 2015 3,960 8 View