Yue Huang

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Questions related from Yue Huang

For the Sterile filtration of Mabs, is it necessary to consider the relation between the filtration speed and PS20/PS80 retention effect?

Content: Fot the Process Characterization of sterile filtration of Mabs, we found out that at the beginning of the sterile filtration of Drug substance, there will be a small portion of protein...

16 May 2018 7,021 1 View

For the Sterile filtration of Mabs, is it necessary to consider the relation between the filtration speed and PS20/PS80 retention effect?

Content: Fot the Process Characterization of sterile filtration of Mabs, we found out that at the beginning of the sterile filtration of Drug substance, there will be a small portion of protein...

16 May 2018 7,229 0 View

We found white-colored micro-particle suspended in the the Mab liquid formulation after fill and finish. can anyone give any insight?

We have encountered a result of some unqualified liquid Mab formulation during a batch manufacturing run. There are several (1-3) white-colored visible micro-particles suspended in the middle of...

19 November 2017 2,689 1 View

There are 3 main peaks for IgG2 when we doing CE. what lead to the third low small peak on the right side by the first 2 main two peaks?

As the question. During the formualation development, one IgG2 of CE result shows 3 main peaks. We assume the first 2 are isoforms. The third one is on the right side of the first 2 with a...

08 September 2017 4,278 3 View

Any guildance on how much temperature variation for long-term stabiltiy of drugs under -40C?

Currently, we are planning on condcut long term stabiltiy for a drug storage under -40 degree C. we are planning on using -40C freezer from thermo Fisher to do the stability study. The IQOQ...

10 March 2017 9,808 1 View