Youssef Aboushady

2 Questions 3 Answers 0 Followers

Questions related from Youssef Aboushady

What can i use as a solvent and base in a suzuki reaction with a sensitive amide in the core?

I tried doing suzuki coupling with general procedure using dioxane:H2O(4:1) and using sodium carbonate as a base at 50C. But it seems that amide bond in my structure breaks. Any recommendations?

13 October 2021 2,872 3 View

O-demethylaton problem ?

We are using for O demethylation Boron tri fluoride methyl sulfide complex our compounds only contain 1 methoxy group..we know by LCMS that our compounds are making complexes with the Oxygen of...

05 April 2018 475 1 View