Yogesh Sharma

8 Questions 25 Answers 0 Followers

Questions related from Yogesh Sharma

How can we turn a short peptide having affinity for some compound into whole cell biosensor?

Greetings, I have a short stretch of 20 aa with strong binding affinity for a compound. I am trying to de some whole cell flourescence or visible biosensing technique based on this peptide. Can...

27 November 2020 8,614 3 View

short peptide whole cell biosensor?

27 November 2020 6,860 3 View

Should one put position restraint on protein backbone during simulations?

Hi, I am studying a transporter protein. X ray crystallographic structure is not known yet. So, i am using homolgy modelled structures for my studies. I am curious if i should put position...

31 July 2020 3,400 1 View

Selecting and rewriting protein trajectory for specific atom groups ?

hey, i am here with two basic questions: I want to perform some analysis on monomers of pentameric protein. There is HSD residue in my protein but when i am performing hydrophobicity related...

22 July 2020 10,090 1 View

Generating protein polymer from monomer?

helllo readers I am trying to generate a protein tetramer from modelled monomer. i tried vmd matrix conversion but most of the available pdbs for protein are considering tetramer as a single...

09 June 2020 8,458 8 View

What are the best tools for aquaporin structure predictions?

Hi everyone I am trying to predict 3D structures of aquaporins for further simulation studies. I have used swissmodel itasser etc. for structure prediction. Although basic characteristic...

11 February 2020 1,977 18 View

What are the best tools for structure predictions?

11 February 2020 7,035 18 View

Dangling bonds in protein terminals?

I am performing protein ligand simulations in Gromacs. In md simulations how can one fix these dangling movements of residues near protein terminals? I think this will interfere in my RMSD or...

14 January 2020 4,193 3 View