Yilin Zhang

7 Questions 11 Answers 0 Followers

Questions related from Yilin Zhang

Patient derived xenograft (PDX) mouse vendor?

Hi Guys, I am looking for a vendor other than Jackson Lab who can provide patient derived xenograft (PDX) NOG mice for drug testing purposes. Thank you!

12 December 2016 6,361 5 View

Any suggestions on the approaches to study exosome?

Specifically how can I isolate exosome from condition medium and ascites, how to break down exosome and study the composition of membrane (such as lipid, protein) as well as contents (miRNA, DNA)....

01 January 2015 6,717 10 View

Which method is most convenient and effiencient for separation proteins (~25kDa) and micelles (~24 nm in diameter,>500kD)?

SEC/GPC-HPLC certainly can do it? How about dialysis vs diafiltration vs TFF?

12 December 2014 8,644 6 View

How can I assess if a protein/Fab/antibody does not undergo conformational change upon a disulfide bond break?

Any techniques to assess if the antibody maintain the original conformation after break one interchain disulfide bond? Thank you.

08 August 2014 7,577 5 View

Is there any way we can measure the progression-free survival using a mouse model?

Generally I used the overall survival and wondered if there is a way to assess PFS as another end-point.

05 May 2014 2,116 0 View

Why are my blots of beta-actin and GAPDH not beautiful after BCA normalization?

see above

04 April 2014 1,270 1 View

What would the internal control be for soluble proteins in condition mediums, or excreted proteins in ECMs?

To explore the protein changes in medium and ECMs.

04 April 2014 4,338 1 View