Woody Lin

7 Questions 15 Answers 0 Followers

Questions related from Woody Lin

Can eQTL be validated by wet-lab experiments?

eQTL = Expression quantitative trait loci (eQTLs) are genomic loci that contribute to variation in expression levels of mRNAs. In other words, a SNP regulating RNA expression level of a gene. Is...

13 December 2017 9,405 3 View

Has anyone compared the gene expression performance between SureSelect RNA and TruSeq Targeted RNA?

I would love to see any comparison results from human genes.

11 April 2014 7,648 0 View

Would RNA quality/quantity be good enough for sequencing when the liver tumor samples are frozen and sliced?

One of my colleague thinks that the RNA quality should be fine for those cryo-sliced liver tumor samples. We just need to use more sliced samples to get enough RNA. Is this correct?

03 April 2014 8,026 4 View

Where do I find the number of common genes between two species?

In trees of life, people have been using the degree of conservation to assign the branches. I am wondering where I can look up for the numbers representing the diversity or commonality between two...

25 November 2013 3,554 5 View

Why are hemoglobin genes very often downregulated in cancers?

I found that mRNA levels of hemoglobin genes are downregulated very often in cancers (attached figure). I have checked Google and Wikigene, but I couldn't find any review article giving it an...

08 November 2013 2,001 7 View

Can metabolomics (LC-MS/MS) distinguish whether amino acids were from metabolites or proteins that are not extracted?

I have liver and serum results from metabolomics analysis. Some of the differential signals were identified as amino acids. I am curious whether the amino acids originated from actual metabolism...

29 January 2013 6,338 8 View

Is it an enzyme or ATP that determines the reaction direction?

ATP determines the direction and an enzyme lowers the activation energy says a textbook. But the forward and backward direction of a bi-directional reaction requires different enzymes. Also some...

20 December 2012 1,513 0 View