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Questions related from Vishnu Kiran
Hi, My drug is sensitive to hydrolysis and we are trying to formulate an o/w nanoemulsion of it. In the stability study, we see a degradation of the drug due to hydrolysis which is not acceptable....
07 July 2018 8,178 4 View
Can I use THF to dissolve the polymer and drug in organic phase for preparing PLGA/PCL nanoparticles by nanoprecipitation method? are there any drawbacks of using THF?
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I have used PLGA (50:50) of different molecular weight ranges (low-high) to entrap a lipophilic drug by nanoprecipitation method. The %EE obtained by HPLC analysis shows nothing has been...
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We are planning to scale up (lab-to-industry) lipid based nano injectable systems. Kindly suggest what sort of processing equipment/technology (Microfluidizer? or any other?) helps meets the...
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I have tried synthesizing PEG-PLGA diblock copolymer using traditional EDC/NHS reaction. The problem here is the yield of the final product. It was around 20%. What could be the reason for this?...
02 February 2015 5,466 7 View