Vishnu m s

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Drugs which are developed by structure based design approach for neurodegeneration (AD, PD, HD etc)?

Apart from the ligand-based technique, with the help of the protein structure file derived from X-RD, lead molecules can be designed in silico. But which all drugs are available or are in any...

13 June 2017 5,750 3 View

What are the current updated methods to perform in-vitro assay of gastric h+/k+ atpase activity?

A strategic method to test enzyme activity and to record the action of small molecules on the enzyme. Also for screening novel molecules by testing its in-vitro inhibitory activity on the gastric...

29 June 2016 9,102 1 View

Reliable computer aided synthesis tools for prediction of synthesis pathway for organic molecules?

As a preliminary in-silico step, so as to get more in depth knowledge about the reaction type and reagents.

23 June 2016 2,170 3 View

Is there an in-vitro assay kit available for the enzyme: gastric h+/k+ atpase?

Novel Proton Pump Inhibitor screening, after in-silico studies.

24 May 2016 5,598 1 View