Vinod D Ramani

3 Questions 7 Answers 0 Followers

Questions related from Vinod D Ramani

How to calculate new human dose based on In-vivo animal study results?

I have performed In-vivo study in rate model for new formulation as well as marketed formulation. Based on results new formulation have significant improvement in all PK parameters. Oral dose...

21 August 2020 2,610 1 View

How to evaluate categorical factors with more than two levels in screening design(eg. plackett burman design)?

I want to use Plackett Burman Design(PBD) for screening the factors. One categorical factor is type of polymer (Type 1, Type 2 and Type 3). In design expert software while selecting categorical...

28 February 2018 2,479 3 View

How to set up HPLC validation for budesonide Dry powder inhelar pharmacokinetic in mice?

Most of the articles I came across for an above sited topic, I found validation with LC-MS, HPLC-MS/MS. Why I can't go with HPLC, though LOQ and LOQ of BUD were 2.29ng/ml and 6.96ng/ml...

31 July 2014 4,169 1 View