Varun Arora

8 Questions 23 Answers 0 Followers

Questions related from Varun Arora

Negative slope in the curve of iron concentration and T2 relaxation?

I've done MRI imaging of iron oxide nanoparticles in phantom gels. The images are showing decreased signal intensities upon increasing the iron concentration, this is due to iron oxide being a...

12 December 2017 7,169 4 View

Cytotoxicity studies of Curcumin loaded nanoparticles in A549 Cels by MTT assay?

Hello, I'm trying to see the cytotoxic effect of curcumin loaded nanoparticles (Iron Oxide) in A549 cell line but the data is absurd. 1. The optical density of wells loaded with nanoparticles...

12 December 2017 6,756 1 View

Why does in FT-IR spectra of uncoated Iron oxide nanoparticles peaks at 2854 and 2926 cm-1 are coming?

I've seen FT-IR spectra of Iron oxide nanoparticles and in many of them peaks at 2854 and 2926 which corresponds to C-H stretching is coming, they haven't coated iron oxide with anything. Can...

04 April 2017 4,773 3 View

What is the best way to form ester bond?

I've synthesized carboxy-terminated nanoparticles, and I want to attach polyethylene glycol (PEG) on the surface of the nanoparticles via ester bond formation between hydroxyl groups of PEG and...

03 March 2017 682 4 View

How to prepare samples for zeta potential reading?

I want to do zeta potential analysis of the samples I've synthesized in different buffers. The samples are aggregating in NaCl, and I want to determine the surface charge on the nanoparticles in...

03 March 2017 532 14 View

Protocol for conjugation of 7-amino 4-methylcoumarin to nanoparticles with free carboxyl groups on the surface?

I'm trying to conjugate 7-amino 4-methylcoumarin (AMC) to nanoparticles with free carboxylate groups on the surface via amide bond formation, but the problem is that AMC is not soluble in water...

03 March 2017 10,002 2 View

How to convert tosylate into amine?

I am trying to synthesize Aminated PEG (NH2-PEG-OCH3) using P-amino benzoic acid to replace the tosyl group on peg-tosylate via nucleophillic substitution reaction. I think both amine and...

07 July 2016 9,079 8 View

EDC/NHS based coupling and stability?

I'm trying to conjugate carboxylic groups terminated nanoparticles with amine terminated polyethylene glycol, I'm using EDC/NHS for the conjugation and DMF as the solvent. The particles after...

03 March 2016 1,795 7 View