Valery Sevrukevitch

4 Questions 2 Answers 0 Followers

Questions related from Valery Sevrukevitch

How to identify LAD in the rat heart?

I use the LAD ligation model in rats to model myocardial infarction. I always pierce the myocardial wall blindly in the area where the LAD should be, but I don't always get an infarction. If...

23 February 2024 3,304 0 View

Animals cannot withstand anesthesia

Hello dear researchers. I am a beginner researcher who faced the following problem. During the experiment on rats, the rats die within 40-60 minutes. This process is accompanied by a drop in...

01 January 1970 4,302 19 View

Problems with the experiment with rats

I encountered the following problem in an experiment. After intraperitoneal injection of urethane to rats at a dosage of 1.3 g/kg, the rats develop hypotension (100/50 mmHg) and bradycardia...

01 January 1970 9,614 3 View

Hemodynamic Instability and Poor Survival in Rat MI Model – Could Inbreeding Be the Cause?

Hello everyone, I’d appreciate your input on an issue we’re facing in our rat myocardial infarction (MI) model. We perform LAD ligation followed by 30 minutes of ischemia and 120 minutes of...

01 January 1970 5,382 1 View