Timothy Graham

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Questions related from Timothy Graham

Are there theoretical limits to how many viable T cells can be derived from peripheral blood donation (e.g., PBMCs) of a single healthy donor?

Immune oncology drug programs are increasingly moving towards use of allogeneic T cells which can be engineered and used with unmatched recipients. Celyad, for instance, recently got clearance...

16 August 2018 1,236 2 View

Any suggestion for a reliable protocol for measuring mtDNA content in mouse tissues as a marker of mitochondrial content?

We are working with mice that have impaired autophagy in different tissues. Autophagy is the principal pathway for turnover/degradation of intact mitochondria. We are measuring mitochondrial...

30 January 2014 4,337 18 View