Best way for crossbreeding cre lox on different background strains (C57BL/6 and BALB/c)?

Hi there, we have to generate a tissue-specific knock-out using the cre loxp system. However, the heterozygote cre line is based on C57BL/6 strain whereas the homozygous floxed mice are on BALB/c...

17 January 2023 9,510 1 View