Simon Kalita-de Croft

3 Questions 14 Answers 0 Followers

Questions related from Simon Kalita-de Croft

Are there any good agents to block gap junctions intracellularly?

Hi guys I am looking for a drug which I can apply through a patch pipette to block gap junctions from the intracellular side. Preferably something with the minimum amount of side effects. Thanks

04 June 2019 5,307 5 View

Does anyone know of a drug that blocks gap junctions from the intracellular side?

Hi everyone I'm currently studying the function of gap junctions, and would like to be able to patch a cell and specifically block its gap junctional output. Does anyone know of a drug I can...

15 September 2016 3,763 4 View

What are the possible reasons why the cesium is not blocking inward-rectifying K+ currents?

I'm patch-clamp recording from neurons that strongly rectify in response to depolarizing current injections. I have tried to eliminate this by using a cesium-based internal. Recent recordings have...

04 February 2015 2,304 3 View