Shobhan Kuila

3 Questions 3 Answers 0 Followers

Questions related from Shobhan Kuila

Immobilizing oxytocin on CM5 surface plasmon resonance Chip?

hello all, I am trying to immobilize oxytocin on a CM5 chip, @200ug/ml concentration, and pH 4.0 acetate buffer. Oxytocin is a 9 amino acid long peptide with a sequence "CYIQNCPLG", the first...

21 March 2023 5,252 2 View

Can presence of 3 consecutive alanine in a sequence disrupts Alpha helix?

i am doing a point mutation of tyrosine to alanine leading to 3 alanine in a row in the peptide sequence. the structure before mutation is alpha helix, will the mutation may lead to disruption of...

23 December 2021 2,551 1 View

If a small molecule inhibitor is binding at an allosteric site on a enzyme with high druggability score on schrodinger but enzyme assay is not wrking?

i have a crystal structure at the allosteric site but need to prove the worth of that allosteric site what experiments can be performed?

26 March 2021 6,399 4 View