I am trying to cleave the tert-butyl ester protecting group from a glutamic acid containing compound with a benzyl group. Please give suggestions?

I have used Reagent K with no luck. The only thing that worked for the deprotection is when TIPS is used, however, it reduces the benzyl group on my compound to a methyl group. I have tried other...

21 February 2019 7,836 3 View