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Questions related from Seketoulie Keretsu
What is the approach used for generic residue numbering of membrane proteins like Serotonin receptors or GPCRs in general? This is particularly challenging when you have a modeled protein that...
25 June 2020 5,222 0 View
There are many papers related to Covid-19 on preprint servers. Most of which are not reviewed. This is particularly more so in computational studies such as Virtual screening, docking and...
05 May 2020 5,298 62 View
Typically, modelling studies are performed with compounds from a single experiment (most of the time), synthesized and evaluated under a defined experimental condition. However, it's not always...
04 February 2020 6,996 1 View
Pymol analysis shows the formation of multiple h-bond with donor nitrogen atom (in figure). Similarly, there have been instances where polar oxygen participates in multiple h-bonds. Kindly explain...
08 January 2019 9,610 4 View
I have a series of irreversible covalent kinase inhibitors. Data shows the covalent interaction of inhibitor with active site residue play crucial role in activity value. Figure shows the most...
08 March 2018 7,511 1 View
From an informatics and analysis point, are there tool available that can be used to extract scaffold from drug/compounds databases such as ChEMBL database? The interest is in comparing scaffolds...
01 August 2017 8,427 0 View
current human kinome is popularly classified into 8 groups based on sequence/structure similarity of the catalytic domains of the kinase. could the human kinome be classified based on any other...
20 July 2017 4,174 1 View
