Seema Patel

6 Questions 10 Answers 0 Followers

Questions related from Seema Patel

What do you think about the impact of 'in vitro passage' on genome stability of pathogens?

Much of in silico pathogen studies involve culture of the clinical isolates, NGS sequencing followed by SNP calling . The novel polymorphisms are associated with drug resistance. But, the genomic...

04 August 2015 2,240 3 View

Why domain of unknown function 'DUF' in proteins are so hard to characterize?

Domain of unknown function (DUFs) form a substantial part of protein domain databases like pfam (about 3,500 DUF families). Many of the DUFs are shared across bacteria, archaea and eukaryota...

04 August 2015 9,645 4 View

How to do metabolomic analysis with bioinformatic tools, especially when you don't have your own data?

The question is little too general. But, I will appreciate suggestions regarding metabolomic data analysis with bioinformatics tools. Where to find reliable metabolome data and how to get started...

26 August 2014 8,093 7 View

Which tools are used by researchers for formatting references as per journal criteria? I do this manually and it's too tedious.

Suggestions are appreciated. I have heard of EndNote, but I have never tried it.

03 April 2014 9,212 11 View

How can I write code for reverse complement of a gene in minus strand, preferably using perl and python?

I have a perl code that generates reverse complement of a Fasta sequence. But, I want it for reference, mutation and their supporting reads in separate columns.

04 March 2014 8,760 6 View

Which method is better for antioxidant assay of plant extracts? DPPH or ABTS? How to decide which method is suitable for a particular extract?

Antioxidant assay of plant extracts

30 December 2012 744 3 View