Rute Barbosa Marques

2 Questions 2 Answers 0 Followers

Questions related from Rute Barbosa Marques

How is it possible that an antibody recognizes the cleaved form but not the full length protein on a denaturating western blot?

I’d like to stain for apoptosis markers cleaved capase3 or cleaved PARP on denaturating western blots. There are multiple antibodies available in the market that claim to recognize the cleaved...

07 July 2015 9,545 3 View

Is the androgen receptor still functional and the pathway still active in prostate cancer tumors that became resistant to enzalutamide or abiraterone?

Also are there androgen receptor mutations, which confer agonistic activity to enzalutamide or abiraterone, like we’ve previously seen with flutamide? I’m interested whether the androgen receptor...

11 November 2013 6,983 3 View