Rodney Rosalia

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Questions related from Rodney Rosalia

Are splenic pre-DC depleted in CD11c-DTR mice (Jung et al., Immunity. 2002 August ; 17(2): 211–220) after DT administration?

In the BM, DT administration seems to deplete all BM-derived DC precursors (Meredith et al., J. Exp. Med. Vol. 209 No. 6 1153-1165), my guess would be that splenic pre-DCs are also depleted in...

10 October 2015 7,718 1 View

What irradiation dose can be applied to selectively deplete/reduce BM dells but not peripheral immune cells in mice?

I would like to reduce the numbers of BM cells through irradiation and reconstitute with new BM cells, or not. The goal would be to study whether peripheral immune cell precursors are able to...

09 September 2015 442 5 View