Ritu Thapa

5 Questions 6 Answers 0 Followers

Questions related from Ritu Thapa

Should the drug release from aqueous solution be 100% before testing drug release from my formulations?

I am performing in vitro drug release studies using franz diffusion cells. my drug is soluble in the release medium (3mg/mL) and for the duration of my studies. I have used 1 mL of 1 mg/mL of drug...

07 July 2024 9,725 1 View

Do anyone have any idea why the R2 values so low in all the rheological models in shear stress vs shear rate ?

I was hoping to find yield stress value using Carson or Herschel bulk key model.. I tried to fit viscosity vs shear rate plots to these models. Howeve, I can’t select these two model in our...

01 February 2024 6,426 0 View

Why are all the R2 values so low in stress vs Shear rate plot? And why can’t the Cassini model be selected in stress vs shear rate analysis?

I would be grateful if anyone could provide the answer to these question. I am using discovery hybrid rheometer HR-3. Thanks a lot

01 February 2024 4,521 0 View

How can I fit my data into rheological models and calculate the rheological parameters from the model?

I have plots of shear stress vs shear rate and viscosity vs shear rate. I want to check which rheological model do my systems (hydrogels) follow and calculate the parameters form the best fitting...

15 November 2023 6,484 7 View

I am using nano ITC.I am not able to get sigmoidal curve . IS it because of no interaction of protein with ligand?

Sample cell was 0.097mM and syringe (1.25, 2.5, 5, 31.25 125mM). At125mM,it was endothermic process and became exothermic at lower concentrations . and enthalphy decreases with the decrease in...

02 May 2016 3,215 7 View