I have been trying to develop a HPLC method for Meropenem trihydrate but failed in many attempts. Are there any suggestions?

I have tried the following mobile phase solvents and ratios of them. I am using 1ml/min FR and 298nm WL. Either I do not get the peak, it is too near the solvent peak, peaks not reproducible or...

10 October 2012 9,614 36 View